Unvaccinated People May Serve As Potential Variant Factories For SARS-CoV-2

Individuals who are not vaccinated against COVID-19 not only risk their health but are also “potential variant factories,” which could jeopardize other’s wellbeing. Experts clarified that the only source of the new COVID variant is the body of an infected person. The more unvaccinated people, the more opportunities for the SARS-CoV-2 to multiply. Since its outbreak, the coronavirus has mutated into different variants such as Alpha, Beta, Gama, and Delta variants, which are more transmissible than the original strain.


Every time a virus mutates, it has the chance of throwing off a variant mutation that is “even more serious” down the road. Sometimes most mutations do not affect the virus, and some can even weaken it. But sometimes viruses also mutate randomly, giving them advantages over their previous version like transmissibility or more efficient replication. These mutated viruses, with an advantage, will outcompete other previous strains and eventually make up the majority of virus particles infecting someone. If that infected person passes the virus to someone else, they’ll pass along the mutant version.


For this mutated version to replicate, an unvaccinated person provides the perfect opportunity. The current vaccines provide immunization against all the variants, but this could change anytime as the pathogen alters its spike proteins. Meanwhile, the World Health Organisation (WHO) warned that the Delta variant of COVID-19 would become the dominant variant of the coronavirus globally in the coming months.


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