SARS-CoV-2 Targets Bone Marrow

Research from the Department of Fundamental Medicine of Far Eastern Federal University has suggested that SARS-CoV-2 could target bone marrow preventing the formation of new erythrocytes. Erythrocytes appear to be a major target for the coronavirus. The loss of erythrocytes may cause damage to the blood vessels, neurons, and internal organs. In more severe cases it could lead to multi-organ failure. The researchers believe that it damages the endothelium in the bone marrow cells.

The early breakdown of RBCs is the initial reaction of the body to SARS-CoV-2. The patient can learn about the pathology by feeling a metallic taste due to the hemoglobin released from erythrocytes in the bloodstream, which finds its way in saliva. People with low hemoglobin are at risk. The researchers also mentioned that the SARS-CoV-2 also induces the destruction of white pulp in the spleen, which is responsible for the production of cells like B &T- lymphocytes.

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Ref link: https://www.eurekalert.org/pub_releases/2020-10/fefu-sma103020.php

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