New Breath Test System for COVID 19 Detection.

Brethonix has developed a rapid breathalyzer/breath analyzer marketed by the name BreFenceTM Go. It is a non-invasive detection system for COVID 19 infection by analyzing the breath and has the ability to detect volatile organic compounds (VOC) in human breath using mass spectroscopy. BreFenceTM comes with a breath sampler, mass spectrometer, and temperature controller attached to a BreathOps Software.


The user needs to exhale into a disposable one-way valve. It requires only a single exhalation from the individual and the BreFenceTM performs real-time analysis for the presence of VOC biomarkers in the breath. The results are obtained immediately within 60 seconds. A positive result indicates the presence of COVID-19 infection. For determining the infection status additional information like patient history, diagnostic data will be required. A negative result does not rule out the presence of COVID-19 and must be treated as presumptive. It should not be used as the sole basis for treatment plans or patient management decisions, including infection control decisions.


By using disposable mouthpieces and one-way valves, it has the potential to be used for mass testing. Operating this device is very easy and does not require any trained personnel. The ongoing pilot study of 180 participants has shown an overall sensitivity of 93% and a specificity of 95%. Brethonix has planned to carry out more clinical trials to validate the accuracy of the device.

The BreFenceTM Go is intended for use in point-of-care settings, hospitals, clinical laboratories, and for mass-screening in high traffic areas. 


Ref Link: https://breathonix.com/covid-19/

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