COVID Booster Shots For Immunocompromised People

The rise in the number of breakthrough infections has become a matter of great concern and urged experts to look for better possibilities. From mix and match of COVID vaccines to the development of a possible third COVID dose, scientists and researchers are looking into various means and methods to make vaccines more effective. That said, the US health agency has now recommended a third mRNA booster shot for people who have a compromised immunity. The announcement comes at a time when Delta variant cases are on the rise in the US.

The majority of COVID vaccines are administered in two doses. However, there are vaccines such as Johnson & Johnson’s Janssen which is a single-shot COVID vaccine. Now, researchers are expanding the horizon and are looking forward to developing a ‘booster’ or a third COVID shot to ensure higher efficacy. Given the increase in the number of new variants, a booster shot is expected to provide better protection against the virus, since it re-expose a person’s immune system to the immunizing antigen, the memory of which (after the previous dose) could have been lost over a period of time.

People with a compromised immunity are at a greater risk of developing COVID-19 infection and are more prone to severe illnesses and even death. That said, immunocompromised individuals are more susceptible to breakthrough infections meaning they can easily contract the deadly virus even after being fully vaccinated. According to Rochelle Walensky, Director of the Centers for Disease Control and Prevention (CDC), At a time when the Delta variant is surging, an additional vaccine dose for some people with weakened immune systems could help prevent serious and possibly life-threatening Covid-19 cases within this population.

The CDC has listed down the type of people who can get their third dose of COVID vaccine.

  1. People receiving treatment for tumours and blood cancer

  2. Advanced or untreated HIV infection

  3. Those who have undergone an organ transplant

  4. People who have received a stem cell transplant and are taking immunosuppressant medications

  5. People dealing with moderate or severe primary immunodeficiency

  6. People who are under high-dose corticosteroids treatment or any other drug that can suppress immunity

Ref Link: CDC



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